Take a close look at this....Now go back and look at the chalazion. Always consider sebaceous cell carcinoma in the differential of recurring chalazion. - General
- Sebaceous carcinoma is more common than squamous cell carcinoma.
- It is rare in patients under 40 years of age. More common in females and Asians
- Location
- It occurs most commonly in the upper eyelid and is extremely rare elsewhere in the body. It can arise from meibomian glands, Zeis glands or sebaceous glands in caruncle.
- Differential Diagnosis
- It may mimic Chalazion or chronic blepharoconjunctivitis.
- Factors associated with poor prognosis
- Upper eyelid origin,
- size greater than 10 millimeters
- Meibomian gland origin
- symptoms greater than 6 months
- infiltrative growth pattern
- pagetoid invasion
- lymphatic or orbital invasion
- Treatment
- Wide local excision with frozen section control
- Excision of the tumor can be performed by a MOHS surgeon, an dermatologist, or an ophthalmic plastic surgeon
|  | Sebaceous Cell Carcinoma involving the right upper, lateral and lower eyelid. |
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